Lafayette County FL Homes For Sale

32066 Zip Code

Discover this 0.5-acre residential corner lot in the Mayo area of Lafayette County. Featuring flat, wooded terrain, the property offers a quiet and natural setting with a balance of privacy and usability for a future home. Located in a peaceful rural area with no HOA restrictions, it provides flexibility for development while still maintaining access to nearby town services, schools, shopping, and essential roadways. The Mayo region is known for its small-town atmosphere, open rural landscapes, and relaxed lifestyle in North Florida, making it an ideal setting for a homesite or long-term land investment. Listing is for land only and comes As Is. Street addresses can be for listing purposes only and vacant land will receive a true street address once improved.

4145 E Us Hwy 27, Mayo

$69,500

Denver Woods Sub SubDv. ⋅ 32008 Zip Code

Build your dream home on this beautiful 5-acre parcel just outside of Branford. You'll appreciate the mature Oak Trees that provide shade and also being on a paved county road. This property offers the perfect setting for country living. Plenty of room for a home, barn, workshop, and animals with easy access to the Suwannee and Santa Fe Rivers. A peaceful North Florida setting with endless possibilities!

7563 Se County Road 405, Branford

$34,999

Pickett Lake Sub SubDv. ⋅ 32008 Zip Code

This vacant lot offers an excellent opportunity to build your future home or make a smart investment. Situated in Pickett Lake Subdivision, the property features 0.46 acres of wooded terrain. Well and septic are required. Enjoy a peaceful setting while remaining conveniently located near shopping, dining, schools, and major highways, providing easy access to city amenities. Whether you’re looking for a private retreat, a development opportunity, or a long-term investment, this lot provides the flexibility and location to suit your needs. Listing is for land only and comes As Is. Street addresses can be for listing purposes only and vacant land will receive a true street address once improved.

160 Se Island Drive, Branford

$20,000

32008 Zip Code

1.6 Acres of lush wooded land just a stones throw from the historic Suwanee River. Create your own private getaway, the opportunities are endless. This property is ideal for a mobile home site or clear a shady spot for your RV. Priced to sell, all information is from the county website, buyer to verify dimensions, agent is related to owner.

Se J M Ridgeway Boulevard, Branford

$3,000,000

6 Beds ⋅ 3 Baths ⋅ 32008 Zip Code

A truly extraordinary and incredibly rare opportunity awaits with this one-of-a-kind 66-acre multi-family estate, privately nestled in a peaceful and picturesque country setting. Whether you’re searching for a high-income-producing investment, a private family compound, an unforgettable hunting and fishing retreat, or a legacy property to enjoy for generations, this remarkable estate offers unmatched versatility, privacy, and endless potential. Surrounded by natural beauty and thoughtfully designed for both comfort and functionality, the property features five residential buildings strategically positioned throughout the acreage to create a sense of privacy and independence. Approximately 57 acres showcase a beautiful mix of open land and wooded surroundings, while an additional privately owned 9-acre portion of Lake Adam provides stunning water views, peaceful lake access, and a breathtaking backdrop rarely found in today’s market. The property is also conveniently located near the famous Suwannee River, making it ideal for outdoor enthusiasts who enjoy boating, fishing, hunting, and year-round recreation. A large open area along the entrance road creates incredible flexibility for future expansion and development opportunities, whether your vision includes additional residences, RV sites, gardens, livestock, recreational amenities, event space, or an expanded retreat-style setting. With over 9,100 square feet of permitted building area, the property is uniquely suited for a wide variety of uses including long-term rentals, short-term vacation rentals, employee housing, multi-generational living, or a private estate compound. Built between 1997 and 2019, the residences feature durable commercial-style modular metal construction with full insulation and quality interior finishes, offering the perfect blend of low-maintenance durability and comfortable living. Each residence is individually equipped with its own private well, septic system, and electric meter, creating convenience, efficiency, and true independence for both owners and tenants. Unlike traditional rental communities, each home enjoys approximately one to two acres of private yard space, providing residents with a spacious and peaceful environment to relax and enjoy the beauty of country living. Community-style amenities further enhance the property’s appeal, including a screened-in swimming pool and private lake access that invite endless relaxation and outdoor enjoyment. Properties offering this level of acreage, infrastructure, privacy, water frontage, and income-producing potential are exceptionally difficult to find. Whether your dream is to create a thriving rental portfolio, establish a private family retreat, develop a destination getaway, or secure a long-term investment with limitless possibilities, this truly remarkable property is ready to make that vision a reality.

401 Se Falcon Road, Branford

$19,950

32066 Zip Code

Discover the perfect opportunity to create your own slice of country living on this beautiful 1-acre residential lot in Lafayette County. Zoned residential, this spacious parcel offers the freedom and flexibility buyers are looking for—whether you're dreaming of building a custom home, starting a mini farm, or simply enjoying more privacy and open space. With plenty of room for a garden, chickens, small livestock, workshop, RV parking, or outdoor entertaining, this property is ideal for those seeking a quieter lifestyle without sacrificing convenience. Enjoy wide-open skies, fresh air, and the peace that comes with having space between you and your neighbors. Bring your builder, your animals, and your vision—this property is ready for your dream home and homestead plans. Opportunities like this don’t last long. Secure your acre of possibility today!

00 Sw Doe Road, Mayo

$20,000

King Sub SubDv. ⋅ 32066 Zip Code

Location! Location! Location! Beautiful parcel of land in Mayo, FL waiting for you to build your dream home. Please verify all information. Measurements are estimates. All offers are welcomed.

San Pedro Avenue, Mayo

$15,000

Canoe Country Sub SubDv. ⋅ 32066 Zip Code

Tucked away in the heart of Old Florida, this 1.44-acre wooded lot offers a rare blend of privacy, nature, and river access. Surrounded by mature trees and alive with twinkling fireflies at night, this peaceful property is perfect for those looking to slow down and enjoy the outdoors. Enjoy community access to the historic Suwannee River, complete with a boat ramp just steps away—ideal for boating, fishing, kayaking, and soaking in the natural beauty of the area. Bring your RV, camper, or ATV and make it your weekend getaway or future homesite. The lot is buildable, with homes and septic systems required to be elevated to meet current floodplain standards, allowing you to design with peace of mind. Located in a quiet, friendly small-town setting, this property offers tranquility without sacrificing a sense of community. An affordable HOA of just $60/year keeps things simple and covers road maintenance, preserving the natural feel of the neighborhood while ensuring easy access. Whether you’re dreaming of a rustic retreat, an outdoor basecamp, or a future elevated home near the river, this property delivers space, serenity, and classic Florida charm.

Nw Fox Run Trail Unit 107, Mayo

$1,005,000

Original Town/Mayo SubDv. ⋅ 32066 Zip Code

This property presents a unique opportunity for business-minded individuals seeking a foothold in a growing North Central Region of Florida. With a generous lot size of 1.46 acres and a 2,623 square foot building, the property offers ample space for a variety of commercial ventures. With a strategic location Halfway between Gainesville and Tallahassee Mayo, the county seat of Lafayette County, places it in a region known as the "Gateway to Growth" and is actively fostering economic development. Businesses here can benefit from a supportive environment and a focus on local prosperity in a rural and peaceful atmosphere. The property's zoning and location near the heart of Mayo make it suitable for a wide range of business possibilities. Entrepreneurs could consider a variety of service-oriented businesses, such as a specialty retail store, a professional office, a catering business, or a skilled trade service. Its proximity to other businesses in the Mayo area, as well as its presence in a region with a strong agricultural and tourism-based economy, suggests potential for a business that serves either the local community or visitors. Prospective buyers are encouraged to consult with Lafayette County's Building and Zoning departments to explore specific land-use regulations and permitting requirements, ensuring their business vision aligns with local codes. This is a rare chance to invest in a property with a strong business potential in a region poised for continued growth.

130 Ne Clyde Avenue, Mayo

$529,000

4 Beds ⋅ 3 Baths ⋅ Devils Elbow Unit 1 SubDv. ⋅ 32008 Zip Code

SUWANNEE RIVER RETREAT--YOUR PRIVATE RIVERSIDE GETAWAY! Welcome to your dream retreat on the high bluffs of the Suwannee River in the serene Hatchbend area! This delightful 4-bedroom, 3-bath home is nestled on a generous 1-acre lot, offering peace, privacy, and panoramic river views. Inside, the home showcases charming rustic décor and a flexible layout. The main level features two cozy bedrooms and a shared bath, along with a fireplace—perfect for gathering on cool evenings. A private suite with its own entrance includes a spacious bedroom, a walk-in closet, and a large picture window overlooking the river, so you can wake up every morning to breathtaking views. On the lower level, you’ll find an additional bedroom and full bath, offering privacy and comfort for guests or extended family. There's also a large enclosed bonus room that can easily be transformed into extra living space, a game room, or the ultimate party room. Outdoor living shines with this property. Enjoy lazy afternoons on the porch swing, cook up a feast in the fully equipped outdoor kitchen and living area, then wind down around the firepit under the stars. A 42-foot aluminum ramp leads to a large floating dock with two jet ski docks, making river access easy and fun. Storage is abundant, with a 30’ x 40’ enclosed garage featuring three roll-up doors—ideal for housing all your toys and tools. There’s also additional covered parking for an RV or boat. The home is wired for a generator and includes an RV hookup. Located just a few miles from the quaint town of Branford, with a population under 800, this peaceful retreat offers small-town charm with big outdoor adventure. Fun starts here! You can begin your day on the water exploring nearby Little River Springs, Ruth Springs and Troy Springs just to the north. Head a little further south to where the Suwanee River meets the Sante Fe River and you will find Ellie Ray’s Campground, a local favorite with live entertaintment, a pool and a party that never ends! Continue up to the mouth of the Ichetucknee, park your boat and jump in the crystal clear water for a swim or head on up to Ginny Springs. Or head back down the Suwannee towards the Gulf Coast and stop off at Hart Springs to enjoy the boardwalk through the Cypress hammock or some cave diving. And be sure to stop by Suwannee Belle Restaurant for some of the best local cuisine. Whether you're looking for a full-time home, a vacation getaway, or a riverfront investment, this Suwannee River gem is a rare find. Tremendous potential for Air BNB! This home is TURN KEY and being sold FULLY FURNISHED--ready for your summer adventures! Schedule your private showing today!

1069 Se Suwannee Trail, Branford